COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING PANCREATIC CANCER
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United States of America Patent
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Nov 19, 2015
app pub date -
May 20, 2015
filing date -
Mar 5, 2008
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Abstract
The present invention provides compositions and methods for treating and diagnosing the presence of solid tumor stem cells in a patient (e.g., based on the presence of c-Met). In certain embodiments, the presence or absence of solid tumor stem cells (e.g., pancreatic solid tumor stem cells) can be determined through the use of a single cells surface marker (e.g., c-Met). The present invention also provides methods for screening candidate compounds (e.g., c-Met antagonists) for the ability to inhibit the tumorigenisis of pancreatic solid tumor stem cells.
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