Methods And Compositions For Prevention Or Treatment Of RSV Infection Using Modified Duplex RNA Molecules

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United States of America Patent

APP PUB NO 20150337311A1
SERIAL NO

14624384

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Abstract

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Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets. The siRNA preferably comprises a sense strand and antisense strand with modified nucleotides.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142-1110

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alvarez, Rene Boxborough, US 25 259
Cole, Geoff Needham, US 3 9
Elbashir, Sayda Cambridge, US 13 223
Meyers, Rachel Newton, US 84 476

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