METHODS OF INHIBITING PRMT5

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United States of America Patent

APP PUB NO 20150344457A1
SERIAL NO

14654213

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Described herein are compounds of Formula (I) useful for inhibiting PRMT5 activity. The planes of Ring AA and Ring BB are between 75° and 105°. Ring AA-M-Ring BB (I)

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Patent Owner(s)

Patent OwnerAddress
EPIZYME INC400 TECHNOLOGY SQUARE 4TH FLOOR CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boriack-Sjodin, Paula Ann Lexington, US 41 1388
Chesworth, Richard Concord, US 171 3995
Duncan, Kenneth W Westwood, US 56 1685
Jin, Lei Wellesley, US 207 2561

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