NEUROTROPHIN-TYROSINE KINASE RECEPTOR SIGNALING

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United States of America Patent

APP PUB NO 20150344535A1
SERIAL NO

14432190

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Abstract

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The invention relates to a method of regulating neurotrophin-tyrosine kinase receptor signaling in a cell comprising modulating the interaction between the juxtamembrane region of the intracellular domain of the neurotrophin receptor p75 and Trk. The invention also relates to compositions comprising compounds which modulate the interaction between the juxtamembrane region of the intracellular domain of the neurotrophin receptor p75 and Trk, and use of the compounds and compositions for the treatment of neurotrophin-Trk signaling related diseases and disorders.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF QUEENSLANDQUEENSLAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BREDY, Timothy William Irvine, US 1 0
COULSON, Elizabeth Jane St Lucia, AU 5 2
MATUSICA, Dusan St. Marys, AU 1 0
SKELDAL, Sune Aarhus C, DK 1 0

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