HUMAN ANTI TSHR ANTIBODIES

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United States of America Patent

SERIAL NO

14790489

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Abstract

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According to one aspect there is provided An isolated human antibody molecule which binds to the TSHR and which reduces ligand-induced stimulation of the TSHR but has no effect on TSHR constitutive activity wherein the isolated human antibody molecule has the characteristic of patient serum TSHR autoantibodies of inhibiting TSH and M22 binding to the TSHR.

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Patent Owner(s)

Patent OwnerAddress
RSR LTDCARDIFF ENGLAND CARDIFF CARDIFF

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Furmani-AK, Jadwiga Cardiff, GB 1 1
Rees-Smith, Bernard Cardiff, GB 2 6
Sanders, Jane Cardiff, GB 13 15

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