STABILIZED STAT3 DECOY OLIGONUCLEOTIDES AND USES THEREFORE
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United States of America Patent
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Issued Date -
Dec 10, 2015
app pub date -
Jun 15, 2015
filing date -
Dec 17, 2009
priority date (Note) -
Abandoned
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Abstract
The present invention is based, at least in part, on novel, unimolecular STAT3 oligonucleotide decoys exhibiting increased in vivo stability as compared to previously known decoys which are effective in inhibiting STAT3 when administered systemically. The invention is also based on pharmaceutical compositions comprising these unimolecular decoys, and methods for using these decoys in the treatment of cancer.
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