METHOD OF MANUFACTURING 1,4-BUTANEDIOL AND MICROBE
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United States of America Patent
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Issued Date -
Dec 10, 2015
app pub date -
Sep 20, 2013
filing date -
Nov 26, 2012
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Abstract
A method of manufacturing 1,4-butanediol, using a microbe and/or a culture thereof, by an enzyme reaction system that uses acyl-CoA reductase, via 3-hydroxybutyryl-CoA, crotonyl-CoA and 4-hydroxybutyryl CoA in this order, wherein the reactivity of the acyl-CoA reductase to 4-hydroxybutyryl CoA is greater than or equal to 0.05 times of the reactivity of the acyl-CoA reductase to 3-hydroxybutyryl-CoA.
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