PROCESS FOR PREPARING AN ENANTIOMERICALLY ENRICHED, DEUTERATED SECONDARY ALCOHOL FROM A CORRESPONDING KETONE WITHOUT REDUCING DEUTERIUM INCORPORATION

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United States of America Patent

APP PUB NO 20150376665A1
SERIAL NO

14789840

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Abstract

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The present invention provides a process for the preparation of enantiomerically enriched, deuterated secondary alcohols of Formula 1-A by employing ketoreductases or carbonyl reductases without reducing deuterium incorporation.

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Patent Owner(s)

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CONCERT PHARMACEUTICALS INC99 HAYDEN AVE SUITE 500 LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eisenreich, Emerich Claremont, US 8 16
Kanamarlapudi, Ramanaiah C Bridgewater, US 19 56
Liu, Xuejun Arcadia, US 36 44
Weissman, Steven A Short Hills, US 15 71

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