HUMAN-DERIVED MUTANTS OF THE dSOD1 GENE IN DROSOPHILA AND METHODS OF MAKING AND USING
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United States of America Patent
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Issued Date -
Jan 7, 2016
app pub date -
Jun 17, 2015
filing date -
Jun 18, 2014
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Abstract
Genetic models of amyotrophic lateral sclerosis (ALS) are described, which can be used to identify novel treatments of ALS and therapeutic targets. Methods for making and using human-derived mutants of the Drosophila dSOD1 gene that model familial ALS are provided. Methods of identifying therapeutic ALS gene targets also are provided.
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