Compositions and Methods for Inhibiting Expression of Eg5 and VEGF Genes

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United States of America Patent

APP PUB NO 20160000819A1
SERIAL NO

14682891

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Abstract

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This invention relates to compositions containing double-stranded ribonucleic acid (dsRNA) in a SNALP formulation, and methods of using the compositions to inhibit the expression of the Eg5 and Vascular Endothelial Growth Factor (VEGF), and methods of using the compositions to treat pathological processes mediated by Eg5 and VEGF expression, such as cancer.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142-1110

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bumcrot, David Belmont, US 49 1259
Sah, Dinah Wen-Yee Boston, US 85 907
Toudjarska, Ivanka Medford, US 32 120

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