Cytoplasmic Expression of Fab Proteins

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United States of America Patent

APP PUB NO 20160002317A1
SERIAL NO

14768678

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Abstract

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The present invention relates generally to antigen binding polypeptides, such as Fab fragments and derivatives thereof, that demonstrate high stability and solubility. The present invention also relates to polynucleotides encoding such polypeptides, to libraries of such polypeptides or polynucleotides, and to methods of using such polypeptides in research, diagnostic and therapeutic applications. For example, the polypeptides can be used in screening methods to identify a polypeptide that binds to a particular target molecule.

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Patent Owner(s)

Patent OwnerAddress
AFFINITY BIOSCIENCES PTY LTDSCORESBY VIC 3179

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beasley, Matthew Fitzroy North, Victoria, AU 14 51
Kiefel, Benjamin Vermont South, Victoria, AU 1 0
Niven, Keith Forest Hill, Victoria, AU 1 0

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