CELL PENETRATING PEPTIDES WHICH BIND IRF5

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United States of America Patent

APP PUB NO 20160009772A1
SERIAL NO

14432977

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention comprises cell penetrating peptides that bind to interferon regulatory factor IRF5 and disrupt the IRF5 homo-dimerization and/or attenuate downstream signaling, and a method for screening peptides that inhibit IRF5. Generally, the cell penetrating peptides of the invention bind human interferon regulatory factor IRF5 (CPP-IRF5).

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Patent Owner(s)

Patent OwnerAddress
F HOFFMANN-LA ROCHE AGSWITZERLAND ZUG ZUG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Demartino, Julie Westfield, US 5 10
Fotouhi, Nader Basking Ridge, US 34 353
Hoffman, Ann Mahwah, US 10 1178
Huang, Kuo-Sen Livingston, US 7 28
Milletti, Francesca New York, US 8 9
Panicker, Sandip Morristown, US 35 225
Srinivasan, Dinesh Freemont, US 5 3
Tan, Seng-Lai Sudbury, US 20 25

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