Compositions and Methods for Inhibiting Expression of Eg5 Gene

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20160017337A1
SERIAL NO

14720685

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the Eg5 gene (Eg5 gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of the Eg5 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Eg5 expression and the expression of the Eg5 gene using the pharmaceutical composition; and methods for inhibiting the expression of the Eg5 gene in a cell.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142-1110

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bumcrot, David Belmont, US 49 1259
Geick, Anke Bayreuth, DE 44 1317
Tan, Pamela Kulmbach, DE 90 1575
Vornlocher, Hans-Peter Bayreuth, DE 97 2123

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