SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS
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United States of America Patent
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Issued Date -
Jan 28, 2016
app pub date -
Mar 12, 2014
filing date -
Mar 15, 2013
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Abstract
Sequestrants of AGE precursors comprise amines separated by 2, 3 or 4 carbons. Sequestrants of AGE precursors can be used as pharmaceutical agents and in pharmaceutical compositions. The sequestrants of AGE precursors are particularly useful binding AGE precursors and dietary dicarbonyls in mammals in the gastrointestinal tract for the treatment of ailments such as diabetic nephropathy, chronic renal disease, atherosclerosis, stroke, cataracts, and Alzheimer's disease.
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