METHODS AND PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND THE PREVENTION OF CARDIOMYOPATHY DUE TO ENERGY FAILURE

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United States of America Patent

SERIAL NO

14764065

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Abstract

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The present invention relates to a method for preventing or treating cardiomyopathy due to energy failure in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of a vector which comprises a nucleic acid sequence of a gene that can restore energy failure. More particularly, the invention relates to a method for preventing or treating a cardiomyopathy associated with Friedreich ataxia in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of a vector which comprises a frataxin (FXN) encoding nucleic acid.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C N R S )75016 PARIS
UNIVERSITE DE STRASBOURG67000 STRASBOURG
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)75013 PARIS

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AUBORG, Patrick Le Kremlin Bicetre, FR 3 7
BOUGNERES, Pierre Le Kremlin Bicetre, FR 12 26
CRYSTAL, Ronald G New York, US 64 946
PUCCIO, Helene Monique Illkirch, FR 5 31

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