METHODS FOR THE TREATMENT OF CANCER

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United States of America Patent

APP PUB NO 20160038498A1
SERIAL NO

14921008

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is directed to methods for treating cancer in a subject, such as a cancer of the endocrine system. In some aspects, the method includes administering to the subject one or more of a polo-like kinase 1 inhibitor, a mouse double minute 2 inhibitor, and/or a mitotic catastrophe inducing compound. In other aspects, the method includes measuring an expression level of one or more markers, including caspase 8 and caspase 9, to assess the functionality of the caspase cascade in the subject.

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Patent Owner(s)

Patent OwnerAddress
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE445 N FIFTH STREET SUITE 600 PHOENIX ARIZONA 85004 85004

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bapat, Aditi Phoenix, US 2 9
Bussey, Kimberly J Phoenix, US 3 9
Demeure, Michael J Phoenix, US 6 9

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