PYRAZOLE DERIVATIVES AS PRMT1 INHIBITORS AND USES THEREOF

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United States of America Patent

APP PUB NO 20160039767A1
SERIAL NO

14775175

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Abstract

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Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.

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Patent Owner(s)

Patent OwnerAddress
EPIZYME INC400 TECHNOLOGY SQUARE 4TH FLOOR CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BORIACK-SJODIN, Paula Ann Lexington, US 41 1388
CHESWORTH, Richard Concord, US 171 3995
MITCHELL, Lorna Helen Cambridge, US 69 1465
MORADEI, Oscar Miguel Burlington, US 32 929
SHAPIRO, Gideon Gainesville, US 125 2170

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