PRODUCTION METHOD FOR COPOLYMER POLYHYDROXYALKANOATE USING GENETICALLY MODIFIED STRAIN OF FATTY ACID ß-OXIDATION PATHWAY
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United States of America Patent
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Feb 11, 2016
app pub date -
Feb 27, 2014
filing date -
Feb 28, 2013
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An object of the present invention is to provide a method for producing poly(3-hydroxybutyrate-co-3-hydroxyhexanoate (P(3HB-co-3HHx)) having a high 3-hydroxyhexanoate fraction using a vegetable oil as a basic raw material. According to the present invention, a method is provided for producing P(3HB-co-3HHx) having a high 3-HHx fraction using a vegetable oil as a basic raw material by disrupting and so forth at least one gene encoding 2-enoyl-CoA hydratase or at least one gene encoding 3-hydroxyacyl-CoA dehydrogenase on a chromosome of a recombinant Cupriavidus necator strain imparted with the ability to produce P(3HB-co-3HHx).
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