Detecting neoplasm

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United States of America Patent

PATENT NO 9994911
APP PUB NO 20160040246A1
SERIAL NO

14775435

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer. Accordingly, provided herein is technology for pancreatic cancer screening markers and other gastrointestinal cancer screening markers that provide a high signal to-noise ratio and a low background level when detected from samples taken from a subject (e.g., stool sample). As described herein, the technology provides a number of methylated DNA markers and subsets thereof (e.g., sets of 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 or more markers) with high discrimination for G1 neoplasms overall and/or at individual tumor sites.

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Patent Owner(s)

  • MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH; EXACT SCIENCES DEVELOPMENT COMPANY, LLC

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahlquist, David A Rochester, US 82 565
Allawi, Hatim T Middleton, US 69 1011
Kisiel, John B Rochester, US 44 145
Lidgard, Graham P Madison, US 129 958
Mahoney, Douglas W Elgin, US 53 193
Taylor, William R Lake City, US 103 1075
Yab, Tracy C Rochester, US 35 143

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