Pharmaceutical composition for oral administration

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United States of America Patent

PATENT NO 9408835
APP PUB NO 20160045479A1
SERIAL NO

14779328

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Abstract

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A pharmaceutical composition containing, as the active ingredient, 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, of which the solubility in an acidic pH region is different from that in a neutral pH region, with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance, is provided. The pharmaceutical composition for oral administration of the present invention contains 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide or a pharmaceutically acceptable salt thereof, and a hydrophilic lubricant, and is useful as a pharmaceutical composition for oral administration with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance.

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Patent Owner(s)

  • ASTELLAS PHARMA INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kojima, Hiroyuki Tokyo, JP 230 2747
Muro, Atsushi Tokyo, JP 13 12
Sakurai, Atsushi Tokyo, JP 199 1638
Takae, Seiji Tokyo, JP 5 37
Tamura, Tetsuya Tokyo, JP 97 1105
Tasaki, Hiroaki Tokyo, JP 7 40

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