4-phenylpiperidines, their preparation and use

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United States of America Patent

PATENT NO 10273243
APP PUB NO 20160046648A1
SERIAL NO

14775532

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Abstract

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The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is H, OH, or halogen; B is a substituted or unsubstituted heterobicycle, pyridazine, pyrazole, pyrazine, thiadiazole, or triazole, wherein the heterobicycle is other than chloro substituted indole; and the pyrazole, when substituted, is substituted with other than trifluoromethyl, or a pharmaceutically acceptable salt thereof.

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Patent OwnerAddress
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK535 WEST 116TH ST NEW YORK NY 10027

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Ping Slingerlands, US 510 5219
Cioffi, Christopher Troy, US 28 474
Conlon, Michael Schenectady, US 26 305
Dobri, Nicoleta New York, US 10 175
Freeman, Emily Voorheesville, US 20 266
Johnson, Graham Sanbornton, US 110 1134
Petrukhin, Konstantin New Windsor, US 34 467
Zhu, Lei Glenmont, US 347 2153

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