OPHTHALMIC COMPOSITIONS WITH OMEGA-3 FATTY ACIDS
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United States of America Patent
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app pub date -
Nov 13, 2012
filing date -
Aug 31, 2012
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Abandoned
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Abstract
A suspension comprising a mixture of omega-3 fatty acids suspended in a formulation vehicle. The formulation vehicle comprises a lightly cross-linked carboxy-containing polymer and a concentration of ionic salt components to provide the suspension with a calculated ionic strength of less than 0.1. The suspension has the following rheological properties, G′>G″ and a suspension yield value of greater than 1 Pa. Also, upon addition of 30 mL of the suspension to a volume of 6 mL to 12 mL of simulated tear fluid, the resulting tear mixture transitions to a liquid form wherein, G″>G′ and the tear mixture has a yield value of less than 0.1 Pa.
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