COMPOSITIONS AND THEIR USES DIRECTED TO HUNTINGTIN
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United States of America Patent
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Issued Date -
Feb 25, 2016
app pub date -
May 11, 2015
filing date -
Jan 26, 2006
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Abstract
Disclosed herein are compounds, compositions and methods for modulating the expression of huntingtin in a cell, tissue or animal. Further provided are methods of slowing or preventing Huntington's disease progression using an antisense compound targeted to huntingtin. Additionally provided are methods of delaying or preventing the onset of Huntingtin's disease in an individual susceptible to Huntingtin's Disease. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders.
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