Method for drug loading hydroxyapatite coated implant surfaces

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United States of America Patent

PATENT NO 9662425
APP PUB NO 20160058922A1
SERIAL NO

14786060

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for loading a hydroxyapatite coated implant with a therapeutic agent including the steps of providing an implant and applying a hydroxyapatite coating on a surface of the implant. The hydroxyapatite coated implant is contacted with a solution including the therapeutic agent. The hydroxyapatite coated implant and solution is heated to temperature of about 60° C. to about 100° C. Pressure is applied to the hydroxyapatite coated implant and solution from about 2 bar to about 10 bar, to load the hydroxyapatite coated implant with the therapeutic agent. An implant made according to the method has sustained therapeutic agent delivery and includes a base and a biomimetic hydroxyapatite coating disposed on a surface thereof.

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Patent Owner(s)

  • STRYKER EUROPEAN HOLDINGS I, LLC

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lilja, Mirjam Farsta, SE 7 148
Procter, Philip Divonne les Bains, FR 14 455
Sörensen, Jan Henrik Kiel, DE 2 148
Sörensen, Torben Christian Mönkeberg, DE 5 150
Steckel, Hartwig Kiel, DE 14 162

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