BIS AZAINOSITOL HAFNIUM COMPLEXES FOR X-RAY IMAGING

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United States of America Patent

APP PUB NO 20160060209A1
SERIAL NO

14786129

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Abstract

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The present invention describes a new class of trinuclear hafnium complexes comprising two hexadentate azainositol carboxylic acid ligands, methods for their preparation and their use as X-ray contrast agents and X-ray diagnostic agents. The claimed compounds can be described by the following Markush formula describing rinuclear hafnium complexes of general formula (I). The following is a compound according to the above Markush formula (example 8).

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITAT DES SAARLANDES66123 SAARBRÜCKEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BERGER, MARKUS BERLIN, DE 102 412
FRENZEL,, III THOMAS BERLIN, DE 1 0
GRAHAM, KEITH BERLIN, DE 51 199
HEGETSCHWEILER, KASPAR INGBERT, DE 5 7
JOST, GREGOR BERLIN, DE 26 34
NEIS, CHRISTIAN ALSWEILER, DE 2 0
PIETSCH, HUBERTUS KLEINMACHNOW, DE 26 58
SÜLZLE, DETLEV BERLIN, DE 43 89

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