Clinical Multimodality-Tools for Pre-And Intraoperative Insulinoma Diagnostics
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United States of America Patent
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Mar 24, 2016
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Jul 25, 2014
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Jul 25, 2013
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Abstract
A chemical compound has the general formula: Ex4-linker-Sar(64Cu)-Fl in which Ex4 is an extendin-4 analog; linker is a polyethylene glycol (PEG) chain, for example formed with four ethylene glycol residues; Fl is a photoluminescent moiety, and Sar(64Cu) is an atom of copper-64 chelated in a sarcophagine moiety is useful as a multimodality imaging agent for detection and localization of insulinoma cells and β-cell masses.
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