TREATMENT AND PREVENTION OF CARDIOVASCULAR DISEASE AND THROMBOSIS

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United States of America Patent

APP PUB NO 20160101062A1
SERIAL NO

14922380

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Abstract

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Provided herein are compositions for the treatment and/or prevention of cardiovascular disease (CVD), and methods of application and use thereof. In particular, the present invention provides treatment and/or prevention of cardiovascular disease with compounds that inhibit the production of TMA in the gut, such as 3,3-dimethyl-1-butanol (DMB) or other compounds represented by Formula I or as shown in FIGS. 20-23.

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Patent Owner(s)

Patent OwnerAddress
THE CLEVELAND CLINIC FOUNDATION9500 EUCLID AVENUE CLEVELAND OH 44195

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hazen, Stanley L Pepper Pike, US 69 227
Levison, Bruce Twinsburg, US 4 23
Wang, Zeneng Shaker Heights, US 16 98

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