AMPHIPHILIC BLOCK COPOLYMERS FOR NUCLEIC ACID DELIVERY
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United States of America Patent
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Dec 28, 2015
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May 15, 2008
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Abstract
The present invention provides a composition comprising vesicles and encapsulated within the vesicles, nucleic acid comprising less than 1000 nucleotides, wherein the vesicles comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block. Methods of forming vesicles and methods of delivering nucleic acid, in particular, iRNA into cells, are also provided.
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