METHOD OF REGULATING CFTR EXPRESSION AND PROCESSING

United States of America Patent

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Oct 8, 2015
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Oct 8, 2014

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Abstract

The present invention relates to methods of reducing ΔF508-CFTR ubiquitination or degradation, or increasing ΔF508-CFTR processing or function in a CF cell comprising contacting the cell with a therapeutic agent that inhibits NEDD8, FBXO2, and/or SYVN1 expression in the cell.

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Patent Owner	Address
UNIVERSITY OF IOWA RESEARCH FOUNDATION	IOWA CENTERS FOR ENTERPRISE 2660 UNIVERSITY CAPITOL CENTRE IOWA CITY IA 52242-5500

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Inventor Name	Address	# of filed Patents	Total Citations
McCray, Paul B	Iowa City, US	8	159
Ramachandran, Shyam	Iowa City, US	7	15

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METHOD OF REGULATING CFTR EXPRESSION AND PROCESSING

Number of patents in Portfolio can not be more than 2000

United States of America Patent

14878829

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14878829

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