Compositions And Method For Treatment Of Ischemic Neuronal Reperfusion Injury

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United States of America Patent

APP PUB NO 20160143886A1
SERIAL NO

15009492

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method and composition for the treatment of ischemic neuronal reperfusion injury are provided. The composition can include a compound which is a combination of dantrolene and a residue of FMOC-valine. This composition can be used to provide a faster and higher CNS penetration than heretofore experienced with dantrolene. In another form, dantrolene may be formulated as a pro-drug, a pro-pro-drug and the like.

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Patent Owner(s)

Patent OwnerAddress
HOWARD UNIVERSITY2400 SIXTH STREET NW SUITE 321 WASHINGTON DC 20059

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Karla, Pradeep K Arlington, US 8 5
Mangat, Harpal S Potomac, US 12 43

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