NANOCARRIER SYSTEM FOR MICRORNAS AND USES THEREOF
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United States of America Patent
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app pub date -
Jun 18, 2014
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Jun 18, 2013
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Abstract
Described herein are novel polyglycerol-amine polymeric nanocarriers in complex with microRNAs and their uses in the treatment of cancer, in particular glioblastoma. Delivery of the polymeric nanocarriers in complex with microRNAs in cell lines and in vivo inhibited cell proliferation, cell cycle progression, cell migration and tumor growth.
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