Nuclear factor-erythroid 2 related factor 2 (NRF2) biosensors and modulators of NRF2

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United States of America Patent

PATENT NO 10054583
APP PUB NO 20160146785A1
SERIAL NO

14435000

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Abstract

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Compositions include nucleic acid sequences encoding the C-terminal fragment of fragment (Seg3) of Nuclear factor-erythroid 2 related factor 2 (Nrf2). These compositions provide a target for identification of novel therapeutics having the ability to modulate the translation of Nrf2. Methods of treating subjects are also provided.

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Patent Owner(s)

  • TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barrero, Carlos A Philadelphia, US 9 15
Merali, Salim Bryn Mawr, US 14 15
Perez-Leal, Oscar M Philadelphia, US 3 2

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