EBV PROTEINS AS MARKERS IN METHODS OF DIAGNOSING CHRONIC FATIGUE SYNDROME (CFS)

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United States of America Patent

APP PUB NO 20160153994A1
SERIAL NO

14896261

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Abstract

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The present invention relates to an in vitro method for diagnosing Chronic Fatigue Syndrome by determining the presence, absence or the amount of at least one marker characteristic of an Epstein-Barr virus (EBV) infection in a sample obtained from the body of an individual. Specifically, the marker characteristic of EBV infection is selected from the group consisting of EBNA1, EBNA3, EBNA4, EBNA6, BZLF1, LMP1 and VP26. Furthermore, the invention relates to a device for the diagnosis of Chronic Fatigue Syndrome, wherein the device comprises a solid phase having immobilized thereon at least one marker or protein fragment thereof, wherein the marker is selected from the group consisting of EBNA1, EBNA3, EBNA4, EBNA6, BZLF1, LMP1 and VP26. In addition, the invention relates to the use of at least one marker or a protein fragment thereof for diagnosis of Chronic Fatigue, wherein the marker is selected from the group consisting of EBNA1 EBNA3, EBNA4, EBNA6, BZLF1, LMP1 and VP26.

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Patent Owner(s)

Patent OwnerAddress
CHARITE-UNIVERSITATSMEDIZIN BERLIN (CHARITE)10117 BERLIN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Priller, Josef Berlin, DE 5 13
Reimer, Ulf Berlin, DE 17 59
Ruprecht, Klemens Berlin, DE 1 0
Scheibenbogen, Carmen Berlin, DE 3 4
Volk, Hans-Dieter Berlin, DE 29 151
Wenschuh, Holger Berlin, DE 5 19

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