METHOD OF REDUCING INTRAOCULAR PRESSURE IN HUMANS
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United States of America Patent
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Issued Date -
Jun 9, 2016
app pub date -
Feb 16, 2016
filing date -
Mar 26, 2010
priority date (Note) -
Abandoned
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Abstract
Provided herein is a method of reducing intraocular pressure (IOP) in humans using N6-cyclopentyladenosine (CPA), CPA derivatives or prodrugs or enhanced cornea permeability formulations of CPA. In one embodiment, the invention is directed to CPA derivatives or prodrugs that are permeable to the cornea. In another embodiment, the invention is directed to uses of certain compounds in human subjects for reducing and/or controlling elevated or abnormally fluctuating IOPs in the treatment of glaucoma or ocular hypertension (OHT).
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