Immunoglobulin expression levels as biomarker for proteasome inhibitor response

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United States of America Patent

PATENT NO 10870889
APP PUB NO 20160177402A1
SERIAL NO

14910668

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.

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Patent Owner(s)

Patent OwnerAddress
ONYX THERAPEUTICS INC2100 POWELL STREET C/O ONYX PHARMAECUTICALS INC EMERYVILLE CA 94608

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Degenhardt, Jeremiah San Mateo, US 5 1
Kirk, Christopher J San Francisco, US 28 109
Kwei, Kevin Mountain View, US 5 26
Loehr, Andrea San Francisco, US 7 105
Tuch, Brian Brisbane, US 4 0

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