Aptamer-Based Biosensing

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United States of America Patent

APP PUB NO 20160178622A1
SERIAL NO

14972399

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure relates to a biosensor device for detecting a predetermined target analyte. The device comprises a substrate. An aptamer bioreceptor for specifically binding to the predetermined target analyte is exposed at a functionalized surface of the substrate. The device also comprises a heat source for heating the substrate via a back surface thereof. The device further comprises a first temperature sensing element for sensing a temperature at the back side of the substrate and a second temperature sensing element for sensing a temperature at the functionalized side of the substrate. The device also comprises a signal processing unit for calculating a heat transfer resistivity value based on temperature values obtained from the first and the second temperature sensing element and the heating power generated by the heat source.

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Patent Owner(s)

Patent OwnerAddress
IMEC VZWKAPELDREEF 75 LEUVEN 3001

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Ceuninck Ward Leuven, BE 11 76
Peeters, Marloes Leuven, BE 2 3
Van, Grinsven Bart Leuven, BE 5 24
Wagner, Patrick Leuven, BE 11 89

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