Effective method for specific gene silencing using artificial small RNA

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United States of America Patent

PATENT NO 9834768
SERIAL NO

14855612

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A nucleic acid molecule comprising a stem-loop structure, a nucleic acid complex comprising the nucleic acid molecule, a composition for delivering a target recognition sequence, and the composition comprising the nucleic acid complex. An artificial small ribonucleic acid of the stem-loop structure stably maintains single-strandedness of a target recognition sequence which interacts with a nucleic acid of interest for a gene of interest of a prokaryote, thereby providing a nucleic acid complex for effective silencing of the gene of interest.

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Patent Owner(s)

  • KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bak, Geunu Daejeon, KR 2 1
Choi, Jee Soo Daejeon, KR 2 1
Kim, Won Kyeong Daejeon, KR 4 1
Lee, Ji Young Daejeon, KR 136 1344
Lee, Younghoon Daejeon, KR 58 630
Park, Hongmarn Daejeon, KR 2 1
Suk, Shinae Daejeon, KR 2 1
Yoon, Yeongseong Daejeon, KR 4 36

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