Compositions and methods for inhibiting hepcidin antimicrobial peptide (HAMP) or HAMP-related gene expression

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United States of America Patent

APP PUB NO 20160186172A1
SERIAL NO

14939985

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Abstract

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The invention relates to lipid formulated double-stranded ribonucleic acid (dsRNA) targeting a hepcidin antimicrobial peptide (HAMP) and/or HAMP-related gene, and methods of using the dsRNA to inhibit expression of HAMP and/or HAMP-related genes.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142-1110

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akinc, Akin Needham, US 113 3427
Bettencourt, Brian Groton, US 134 658
Charisse, Klaus Acton, US 73 449
Foster, Don Attleboro, US 19 81
Kuchimanchi, Satyanarayana Acton, US 61 396
Maier, Martin A Belmont, US 82 746
Milstein, Stuart Cambridge, US 133 755
Rajeev, Kallanthottathil Wayland, US 35 82
Sehgal, Alfica Allston, US 46 123

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