Importance

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Abstract

Disclosed is a system and method for automating the performance of a conjugate or sandwich assay, and a cassette for use with the system. The cassette comprises a fluid conduit and one or more chambers in the fluid conduit, from which a measurement may be acquired from a sample using a cassette reader device. Sample and reagent fluids may be caused to flow along the fluid conduit to perform the assay and control over the progress of the assay may be exerted at least in part by the arrangement of chambers in the fluid conduit. Also disclosed is a tablet or bead for use with the assay system, which may be incorporated in the cassette. The tablet or bead may comprise one or more reagents to be used in the assay, in a soluble matrix. Use of an acridan or acridinium ester label may enable a sensitive measurement to be rapidly acquired. The assay may be configured to be performed by a clinician at the point of use or care.

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First Claim