THERAPEUTIC COMPOSITIONS INCLUDING IRON CHELATORS AND USES THEREOF
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United States of America Patent
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Issued Date -
Jul 14, 2016
app pub date -
Jan 7, 2016
filing date -
Jan 8, 2015
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Abstract
Disclosed herein are methods and compositions for the treatment and/or prevention of diseases or conditions comprising administration of at least one iron chelator, and/or naturally or artificially occurring derivatives, analogues, or pharmaceutically acceptable salts thereof, alone or in combination with one or more active agents (e.g., an aromatic-cationic peptide). The present technology provides compositions related to aromatic-cationic peptides linked to at least one iron chelator and uses of the same. In some embodiments, the aromatic-cationic peptide comprises D-Arg-2′6′-Dmt-Lys-Phe-NH2.
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