Immunogenic middle east respiratory syndrome coronavirus (MERS-CoV) compositions and methods

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United States of America Patent

PATENT NO 10751410
APP PUB NO 20160206729A1
SERIAL NO

15023629

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Abstract

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Disclosed herein are nanoparticles containing MERS virus proteins in polymer structures, and compositions containing the nanoparticles formulated for administration as immunogenic compositions. Also provided herein are vector constructs encoding the proteins, and host cells containing the vector constructs. The disclosure also includes methods of making the nanoparticles and administering them to vertebrates, including methods of inducing immune responses to MERS that reduce or prevent infection by the virus.

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Patent Owner(s)

Patent OwnerAddress
NOVAVAX INC700 QUINCE ORCHARD ROAD GAITHERSBURG MD 20878

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Ye Gaithersburg, US 353 2493
Massare, Michael Gaithersburg, US 8 144
Smith, Gale Gaithersburg, US 70 738

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