Nanofluidic channels with gradual depth change for reducing entropic barrier of biopolymers

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United States of America Patent

PATENT NO 9983190
SERIAL NO

15085394

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Abstract

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A device for passing a biopolymer molecule includes a nanochannel formed between a surface relief structure, a patterned layer forming sidewalls of the nanochannel and a sealing layer formed over the patterned layer to encapsulate the nanochannel. The surface relief structure includes a three-dimensionally rounded surface that reduces a channel dimension of the nanochannel at a portion of nanochannel and gradually increases the dimension along the nanochannel toward an opening position, which is configured to receive a biopolymer.

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Patent Owner(s)

  • INTERNATIONAL BUSINESS MACHINE CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lin, Qinghuang Yorktown Heights, US 151 2188
Stolovitzky, Gustavo A Riverdale, US 76 869
Wang, Chao Ossining, US 804 2579
Wang, Deqiang Ossining, US 41 349

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