BIODEGRADABLE POLYMER AND TISSUE COMBINATIONS
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United States of America Patent
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Apr 4, 2016
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Aug 26, 2004
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A biodegradable bioprosthesis can include a biodegradable tissue and a biodegradable polymer combined with the biodegradable tissue. The biodegradable tissue can be non-crosslinked tissue, EDC crosslinked tissue or tissue crosslinked using biodegradable crosslinker. The biodegradable polymer can be a crosslinked polymer and/or synthetic polymer. The bioprosthesis can include a bioactive agent (rifampin). The biodegradable tissue and biodegradable polymer can form a drug delivery patch having the bioactive agent. The bioactive agent can be an antimicrobial. The biodegradable tissue can be decellularized. A method of making the biodegradable bioprosthesis can include treating the biodegradable tissue with a fluid having the biodegradable polymer. A method of implanting a biodegradable bioprosthesis can include implanting the bioprosthesis in a subject, where the bioprosthesis is implanted for repairing a hernia and/or the bioprosthesis inhibits post-operative adhesions.
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