18F -GLUTATHIONE CONJUGATE AS A PET TRACER FOR IMAGING TUMORS OR NEUROLOGICAL DISORDERS THAT OVEREXPRESS L-PGDS ENZYME

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United States of America Patent

APP PUB NO 20160228584A1
SERIAL NO

14957081

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Abstract

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A PET tracer for imaging tumors or neurological disorders that overexpress L-PGDS enzyme is provided. The present invention have prepared a glutathione conjugate of fluorine-18-labeled fluorobutyl ethacrynic amide using an acceptable amount of radioactivity that is capable of binding to L-PGDS and can be used for in vitro and in vivo imaging studies.

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NATIONAL TSING HUA UNIVERSITYNO 101 SEC 2 KWANGFU RD HSINCHU CITY 30013

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HUANG, Ho-Lien Hsinchu, TW 5 7
HUANG, Ying-Cheng Hsinchu, TW 2 0
LIN, Kun-Ju Hsinchu, TW 2 0
YEH, Chun-Nan Hsinchu, TW 13 70
YU, Chung-Shan Hsinchu, TW 7 8

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