SINGLE CELL ANALYSIS BY POLYMERASE CYCLING ASSEMBLY

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United States of America Patent

APP PUB NO 20160230236A1
SERIAL NO

15133932

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides a method of making measurements on individual cells of a population, particularly cells that have identifying nucleic acid sequences, such as lymphoid cells. In one aspect, the invention provides a method of making multiparameter measurements on individual cells of such a population by carrying out a polymerase cycling assembly (PCA) reaction to link their identifying nucleic acid sequences to other cellular nucleic acids of interest. The fusion products of such PCA reaction are then sequenced and tabulated to generate multiparameter data for cells of the population.

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Patent Owner(s)

Patent OwnerAddress
ADAPTIVE BIOTECHNOLOGIES CORP1551 EASTLAKE AVE E SUITE 200 SEATTLE WA 98102

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Faham, Malek Pacifica, US 97 5030
Willis, Thomas San Francisco, US 40 3288

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