COMPOSITION FOR TREATING OR PREVENTING ERECTILE DYSFUNCTION COMPRISING LDD175 AS ACTIVE INGREDIENT
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United States of America Patent
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Issued Date -
Aug 18, 2016
app pub date -
Jan 13, 2016
filing date -
Jan 14, 2015
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Abstract
The present invention relates to a pharmaceutical composition for treating or preventing erectile dysfunction, containing LDD175 as an active ingredient. Furthermore, the present invention relates to a co-administration preparation for treating or preventing erectile dysfunction, containing LDD175 and a PDE5 inhibitor as active ingredients. The LDD175 of the present invention has an excellent corporal smooth muscle relaxation effect, and thus significantly improved erectile function. Since the LDD175 of the present invention acts on BKCa channels, and thus is expected to have little adverse cardiovascular effects. The LDD175 of the present invention exhibits an erectile dysfunction therapeutic ability equivalent to that of udenafil, which is a PDE5 inhibitor, and showed a synergistic corporal smooth muscle relaxation effect when being co-administered with udenafil.
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