Tau antisense oligomers and uses thereof

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United States of America Patent

PATENT NO 10799523
APP PUB NO 20160237427A1
SERIAL NO

15016169

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Abstract

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The present invention relates to oligomer compounds (oligomers), which target Tau mRNA in a cell, leading to reduced expression of Tau protein. Reduction of Tau protein expression is beneficial for the treatment of certain medical disorders, e.g., a neurological disorder.

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Patent Owner(s)

Patent OwnerAddress
F HOFFMANN-LA ROCHE AGSWITZERLAND ZUG ZUG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Jeffrey M Medway, US 27 452
Cacace, Angela M Higganum, US 17 36
Høg, Anja Mølhart Hillerød, DK 13 159
Hagedorn, Peter Horsholm, DK 42 97
Jensen, Marianne Lerbech Køge, DK 15 50
Li, Dong East Lyme, US 584 9113
Mercer, Stephen E Middleton, US 17 80
Nielsen, Niels Fisker Kgs. Lyngby, DK 20 221
Olson, Richard E Orange, US 142 1446

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