High-throughput single-cell analysis combining proteomic and genomic information

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United States of America Patent

PATENT NO 10697010
APP PUB NO 20160244828A1
SERIAL NO

15046225

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Abstract

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Disclosed herein are methods for single-cell sequencing. In some examples, the methods include enriching a sample comprising a plurality of cells for cells of interest to produce an enriched cell sample; isolating one or more cells of interest in the enriched cell sample; and obtaining sequence information of one or more polynucleotides from each of the one or more isolated cells. Obtaining sequence information may include generating a molecularly indexed polynucleotide library from the one or more isolated cells. Enriching the sample may include focusing cells of interest in the sample using acoustic focusing.

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Patent Owner(s)

  • BECTON DICKINSON AND COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mason, Clark Franklin Lakes, US 4 147
Yu, Liping San Jose, US 21 278

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