Delayed release drug formulation

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 10799515
APP PUB NO 20160250232A1
SERIAL NO

15028863

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Abstract

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In a delayed release formulation comprising a core containing a drug and a delayed release coating for providing intestinal release, release of the drug in the colon is accelerated by including an isolation layer between the core and the delayed release coating. The delayed release coating comprises an inner layer and an outer layer. The outer layer comprises a pH dependently soluble polymeric material which has a pH threshold at about pH 5 or above. The inner layer comprises a soluble polymeric material which is soluble in intestinal fluid or gastrointestinal fluid, said soluble polymeric material being selected from the group consisting of a polycarboxylic acid polymer that is at least partially neutralised, and a non-ionic polymer, provided that, where said soluble polymeric material is a non-ionic polymer, said inner layer comprises at least one additive selected from a buffer agent and a base.

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Patent Owner(s)

  • TILLOTTS PHARMA AG

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Basit, Abdul Waseh Harrow, GB 19 79
Bravo, Gonzalez Roberto Carlos Binningen, CH 5 22
Buser, Thomas Nuglar, CH 20 452
Freire, Ana Cristina Riverside Wharf, GB 6 30
Varum, Felipe Jose Oliveira Basel, CH 3 13

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