FORMULATION FOR GONADOTROPINS
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United States of America Patent
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Issued Date -
Sep 1, 2016
app pub date -
Oct 31, 2014
filing date -
Nov 12, 2013
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Abstract
The present invention relates to a stable composition for gonadotropins. It provides a composition useful for stabilization of gonadotropins while preventing aggregation, dissociation, fragmentation and formation of oxidized species variants in solution for injection. Thus, it prevents instability of protein or polypeptide molecules caused due to aggregation or fragmentation or oxidation during or after formulation. Also, it provides a pharmaceutical composition of gonadotropins, which can be therapeutically used for the treatment of various indications either in single-dose form or in multi-dose form.
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